Total Testosterone

The overall level of the main male sex hormone. Low testosterone and an underactive thyroid can both cause fatigue and weight gain, so seeing them together helps tell the two apart.

Free Testosterone

The share of testosterone not bound to proteins and ready for your body to use. It can be low even when total testosterone looks normal, which can explain low energy or drive.

Prostate Specific Antigen (PSA)

A protein made by the prostate, included as this panel's prostate check. It gives a reference point for prostate health that sits alongside your testosterone results.

Estradiol

Men make estradiol mostly from testosterone. Levels that are too high or too low are linked with low libido, weight gain and mood changes, so it is read here against total testosterone and SHBG.

Sex Hormone Binding Globulin (SHBG)

A protein that binds testosterone and estradiol. Thyroid hormone raises SHBG, so thyroid changes can shift how much free testosterone you have, which is why it links the two halves of this panel.

Thyroid Stimulating Hormone (TSH)

The signal your pituitary sends to the thyroid. It rises when the thyroid is underperforming and falls when it is overactive, which makes it the anchor for reading free T4 and free T3 on this panel.

Free Triiodothyronine (FT3)

The active form of thyroid hormone that sets how fast your cells burn energy. Most of it is converted from free T4, so low T3 with normal T4 can point to slow conversion rather than a thyroid problem.

Free Thyroxine (FT4)

The main hormone your thyroid releases into the blood. Alongside TSH, it shows whether your thyroid is keeping up with your body's demand or falling behind, a common cause of tiredness and weight gain.

DHEA-S

An adrenal hormone your body uses to make testosterone and estrogen. Read with total testosterone, it helps show whether low energy or drive has an adrenal side as well as a thyroid or testicular one.