Liver Health

What is Liver Function Testing and Why Is It Important

Did you know your liver performs over 500 functions? From detoxifying your blood to regulating your metabolism. Liver function tests (LFTs) are the most common way doctors evaluate liver health, detect early issues, and monitor how your liver responds to diet, alcohol, medications, or lifestyle changes.

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Dr. Alan Farrell
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December 9, 2025
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4 min
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But today, it’s not just clinicians who want this information. Millions of people are proactively tracking their own health markers. Whether it’s monitoring the effects of alcohol, checking on supplements or medications, or simply wanting a clearer picture of long-term health, more individuals are looking for direct access to their liver numbers without waiting for a doctor’s appointment.

At-home liver function tests now make this possible with less money and time needed. With a simple finger-prick sample, you can check your levels, spot changes early, and track trends over time.

This guide breaks down everything you need to know about liver function testing, what your results mean, and when you should consider retesting.

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What Is a Liver Function Test (LFT)?

A liver function test is a blood test that measures a group of enzymes and proteins that reflect how well your liver is working. These markers help detect:

  • Early liver injury
  • Fatty liver disease
  • Alcohol-related liver stress
  • Bile duct issues
  • Metabolic dysfunction
  • Inflammation
  • Medication-related liver effects

Each biomarker reveals something slightly different about liver function… together they provide a complete picture.

The Core Liver Enzymes Explained

ALT (Alanine Aminotransferase)

ALT is one of the first markers to rise when liver cells are inflamed or under stress. Common causes of elevated ALT:

  • Fatty liver / metabolic dysfunction
  • Alcohol use
  • Medications (e.g., Tylenol, statins)
  • Hepatitis
  • Weight gain + insulin resistance

AST (Aspartate Aminotransferase)

AST increases when liver, muscle, or heart tissue is under stress. It’s useful when interpreted alongside ALT. AST:ALT ratio helps identify:

  • Alcohol-related liver stress
  • Fatty liver disease
    Muscle injury
  • Liver inflammation patterns

GGT (Gamma-Glutamyl Transferase)

GGT is a sensitive marker of bile duct function and oxidative stress. It often rises before other enzymes. High GGT can indicate:

  • Alcohol use or recent drinking
  • Early metabolic dysfunction
  • Bile duct issues
  • Medication effects
    Chronic oxidative stress

Most people with early liver dysfunction feel no symptoms at all. This is why LFTs are often the first sign of:

What These Tests Can Reveal — Even Before You Feel Symptoms
Category What the markers reveal
Metabolic dysfunction (insulin resistance) ALT and GGT can elevate years before blood sugar markers (HbA1c) change.
Fatty liver disease (NAFLD & MASLD) ALT + GGT patterns are often highly predictive and can be reversible with lifestyle changes.
Alcohol-related liver stress AST:ALT ratio and GGT together give the clearest picture of alcohol impact.
Medication effects Many prescriptions (for example, statins, antifungals, anticonvulsants) require periodic liver monitoring.
Oxidative stress and inflammation GGT is a sensitive marker of cellular stress and oxidative burden.
Normal Ranges for Common Liver Markers
Marker Typical range What it means
ALT Men: <55 U/L, Women: <45 U/L Higher = liver cell injury
AST Men: <45 U/L, Women: <35 U/L Higher = liver or muscle stress
GGT Men: <14 U/L (Optimal), 14–27 (Elevated) — Women: <9 U/L (Optimal), 9–17 (Elevated) Higher = alcohol use, oxidative stress

Ranges vary slightly by lab; but the best way to understand what a healthy baseline for your liver is, is to test over time. 

At-Home Liver Testing: How It Works

We offer at-home liver function testing designed to make monitoring simple:

  1. Collect a finger-prick sample using the included kit
  2. Send it to our CLIA-certified lab in a prepaid envelope
  3. Results are shared within 3 days after sample reaches the lab
  4. Track trends over time inside your dashboard

Receive next-step recommendations and insights based on your enzyme patterns.

When Should You Test Your Liver Function?

Experts recommend liver function tests if you:

  • Drink alcohol regularly
  • Have elevated HbA1c or blood sugar
  • Carry extra weight around your midsection
  • Have family history of metabolic or liver disease
  • Take medications processed by the liver
  • Are trying to reverse fatty liver
  • Have elevated cholesterol or triglycerides
  • Want to monitor long-term health proactively
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The Most Important Metric Many People Miss: Trends Over Time

One-time numbers are helpful, but patterns tell the real story.

We track:

  • Month-to-month ALT changes
  • AST:ALT ratio trends
  • GGT response to alcohol reduction
  • Overall metabolic patterns

This is where early intervention becomes possible.

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